Potentiometric Titration of an Acid with a Strong Base

1. Aim

To complete the Year 3 syllabus practical potentiometric titration of an acid with a strong base using an instructor-approved method or dataset. Actual analyte, measurements, and result must be entered in the student record.

2. Requirements

Instructor-approved sample and reference standard, validated method, instrument and calibration records, blank and controls, observation sheet, calculator or graphing aid, protective equipment, and chemical waste route. Confirm sample identity from its label and use the college method sheet for reagent quantities, concentrations, wavelengths, pH, and temperature. Acceptance criteria are to be recorded from the assigned current monograph or approved college method in the student record.

3. Theory

A pH electrode measures a potential related to hydrogen-ion activity. During titration, pH changes with added base; a sharp inflection or derivative peak can locate an equivalence volume. The endpoint is method-specific and should be checked against electrode calibration, mixing, and a complete titration curve.

4. Procedure

Confirm sample identity, method version, hazards, instrument calibration, and required controls.
Record raw standards, blanks, sample readings, units, and any preparation or dilution factors.
Follow the verified laboratory method under instructor supervision, or analyze its supplied dataset.
Check pH meter calibration and base standardization. Plot pH against base volume, inspect the inflection or derivative, and use the accepted endpoint to calculate the sample amount.
Check the fit, control recovery, and measurement range before applying a formula.
Report the calculation with units, method limitations, and unresolved details recorded in the student record.

5. Observation and calculation

Student record field	Entry
Case or product	Record here
Method	Record here
Observation	Record here
Inference	Record here
Supervisor check	Record here
Outcome	Record here

Assumed values for calculation practice only: An assumed endpoint occurs at 10.0 mL of assumed 0.100 mol/L base for an assumed monoprotic acid sample. Assumed moles = 0.0100 L × 0.100 mol/L = 0.00100 mol. All inputs are invented. Each invented input and output is assumed, not a reagent instruction or actual laboratory result.

6. Output or final result

Submit a labelled pH titration curve, calculations where justified, and a conditional conclusion. Record the supervised outcome here.

Teaching-lab safety: Use instructor-supervised chemical handling and the approved disposal method. No assumed value here authorizes a preparation or analytical release decision.

This page is a supervised-activity guide; it does not report a completed case.

7. Sources

← Conductometric Titration of a Mixture of Acids with a Strong BaseEstimation of Drugs by Fluorimetric Technique →

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