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Biopharmaceutics and Pharmacokinetics Practicals

PharmacoLearn Year 4 syllabus lists 16 practical entries. All 16 have individual articles and labelled diagrams. Human, animal, and ex vivo work requires ethical authorization. No assignments are included.

Practical exercises

1. 1. Improvement of Dissolution of Slightly Soluble Drugs

   To study year 4 biopharmaceutics 1 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

2. 2. Comparison of Dissolution of Two Marketed Products of the Same Drug

   To study year 4 biopharmaceutics 2 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

3. 3. Influence of Polymorphism on Solubility and Dissolution

   To study year 4 biopharmaceutics 3 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

4. 4. Protein Binding of Highly and Poorly Bound Drugs

   To study year 4 biopharmaceutics 4 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

5. 5. Extent of Plasma Protein Binding at Different Concentrations

   To study year 4 biopharmaceutics 5 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

6. 6. Bioavailability of Common Drugs in an Animal or Human Model

   To study year 4 biopharmaceutics 6 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

7. 7. Calculate Ka, Ke, Half-Life, Cmax, AUC, AUMC and MRT

   To study year 4 biopharmaceutics 7 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

8. 8. Bioavailability from Urinary Excretion Data for Two Drugs

   To study year 4 biopharmaceutics 8 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

9. 9. AUC and Bioequivalence from Given Data for Two Drugs

   To study year 4 biopharmaceutics 9 using supervised records and report the supported outcome. Actual case, sample, and result must be entered in the student rec

10. 10. In Vitro Absorption Studies

    To complete the syllabus requirement year 4 biopharmaceutics 10 through an approved supervised record. Actual work and results must be entered in the student re

11. 11. Bioequivalence Studies of Marketed Drugs

    To complete the syllabus requirement year 4 biopharmaceutics 11 through an approved supervised record. Actual work and results must be entered in the student re

12. 12. Absorption in Animal Inverted Intestine

    To complete the syllabus requirement year 4 biopharmaceutics 12 through an approved supervised record. Actual work and results must be entered in the student re

13. 13. Effect of Contact Time on Plasma Protein Binding

    To complete the syllabus requirement year 4 biopharmaceutics 13 through an approved supervised record. Actual work and results must be entered in the student re

14. 14. Metabolic Pathways from Elimination Kinetics Data

    To complete the syllabus requirement year 4 biopharmaceutics 14 through an approved supervised record. Actual work and results must be entered in the student re

15. 15. Elimination Half-Life from Blood and Urinary Data

    To complete the syllabus requirement year 4 biopharmaceutics 15 through an approved supervised record. Actual work and results must be entered in the student re

16. 16. Determination of Renal Clearance

    To complete the syllabus requirement year 4 biopharmaceutics 16 through an approved supervised record. Actual work and results must be entered in the student re

Theory notes: Pharm D Year 4, 4.5 Biopharmaceutics and Pharmacokinetics

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